Dr. Chanchal Kumar

Assistant Professor

Work Experience

Assistant Professor in Department of Forensic Science, Guru Ghasidas Vishwavidyalaya from 14-10-2019 Assistant Professor (contract), Department of Biotechnology, AIIMS, New Delhi from 18-03-2018 to 3-10-2019 Research Associate , Department of Biotechnology, All India Institute of Medical Sciences, New Delhi from- 30-04-2014 to 31-01-2018. Teaching Assistant at Department of Biochemistry, M.S. University of Baroda, 2012-¬2013 Teaching Assistant at Department of Biochemistry, M.S. University of Baroda, 2010¬-2011

Area of Specialization

Molecular Biology, Genetic Engineering, Metabolic Engineering, Biochemistry, DNA based Sensors, Infection Biology, Forensic genetics and profiling

Projects & Patents

Synthesis and yield enhancement of pyrroloquinoline quinone through cloning and overexpression of pqq gene cluster in Enterobacter asburiae PSI3. UGC Strat Up grant (Rs. 10 lac)-2021-2023

Education

2014-2018- Post Doctorate, Department of Biotechnology, AIIMS, New Delhi 2013- Ph.D. in Biochemistry, Department of Biochemistry, The M.S. University of Baroda. 2007- Master of Philosophy (M. Phil) in Life Sciences, School of Life Sciences, Jawaharlal Nehru University, New Delhi. 2004 -M.Sc. in Biotechnology, Department of Microbiology and Biotechnology Center. The M.S. University of Baroda, Vadodara.

Achievments/Awards/Honors

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Publications

1. Megha Yadav, Blessi N. Uikey, Shantnu Singh Rathore, Priyanka Gupta, Diksha Kashyap, Chanchal Kumar, Dhananjay Shukla, Vijayamahantesh, Arvind Singh Chandel, Bharti Ahirwar, Ashish Kumar Singh, Shashi Shekhar Suman, Amit Priyadarshi and Ajay Amit (2023) Role of cytokine in malignant T-cell metabolism and subsequent alternation in T-cell tumor microenvironment. Frontiers in Oncology. DOI: 10.3389/fonc.2023.1235711 (I.F.-4.7) 2. Abhijeet Dhiman, Chanchal Kumar, Subodh Kumar Mishra, Kriti Sikri, Ishara Datta, Pradeep Sharma, Tej P. Singh, Sagarika Haldar, Neera Sharma, Anjali Bansal, Yusra Ahmad, Amit Kumar, Tarun Kumar Sharma, and Jaya Sivaswami Tyagi, (2019)Theranostic application of a novel g-quadruplex-forming DNA aptamer targeting malate synthase of Mycobacterium tuberculosis, Molecular Therapy Nucleic Acid., ISSN: 2162-2531 (2019), 18: 661-672, DOI: 10.1016/j.omtn.2019.09.026. (I.F.-10.18) 3. Saurabh Sharma, Priyanka Kumari, Atul Vashist, Chanchal Kumar, Malobi Nandi and Jaya Sivaswami Tyagi (2019) Cognate sensor kinase‐independent activation of Mycobacterium tuberculosis response regulator DevR (DosR) by acetyl phosphate: Implications in anti‐mycobacterial drug design, Molecular Microbiology., ISSN: 1365-2958 , (2019), 111 (5): 1182-1194, DOI: 10.1111/mmi.14196. (IF- 3.8) 4. Kriti Sikri, Priyanka Duggal, Chanchal Kumar, Sakshi Dhingra Batra, Atul Vashist, Ashima Bhaskar, Kritika Tripathi, Tavpritesh Sethi, Amit Singh and Jaya Sivaswami Tyagi (2018) Multifaceted remodeling by vitamin C boosts sensitivity of Mycobacterium tuberculosis subpopulations to combination treatment by anti-tubercular drugs Redox Biology., ISSN:2213-2317,(2018), 15: 452-466, DOI: 10.1016/j.redox.2017.12.020 . (IF- 11.8) 5. Chanchal Kumar, Jitendra Wagh, G. Archana, G. Naresh Kumar (2016) Sucrose dependent mineral phosphate solubilization in Enterobacter asburiae PSI3 by heterologous overexpression of periplasmic invertases, World Journal of Microbiology and Biotechnology., ISSN: 0959-3993 , (2016), 32 :194 , DOI: 10.1007/s11274-016-2153-x. (IF-4.27) 6. Jitendra Wagh, Kumar Chanchal, Shah Sonal, Bhandari Pravena, G. Archana, G. Naresh Kumar (2016) Inoculation of genetically modified endophytic Herbaspirillum seropedicae Z67 endowed with gluconic and 2-ketogluconic acid secretion, confers beneficial effects on rice (Oryza sativa) plants, , Plant and Soil., ISSN: 0032-079X, (2016), 409 (1):51-64, DOI: www.jstor.org/stable/44245215, (IF-5.44) 7. Kavita Yadav, Chanchal Kumar, G. Archana, G. Naresh Kumar (2014) Artificial citrate operon and Vitreoscilla hemoglobin gene enhanced mineral phosphate solubilizing ability of Enterobacter hormaechei DHRSS, Applied Microbiology and Biotechnology., ISSN: 0175-7598 , (2014), 98: 8327–8336, DOI: 10.1007/s00253-014-5912-3. (IF- 4.8) 8. Kavita Yadav*, Chanchal Kumar*, G. Archana, G. Naresh Kumar (2014) Pseudomonas fluorescens ATCC 13525 containing an artificial oxalate operon and Vitreoscilla hemoglobin secretes oxalic acid and solubilizes rock phosphate in acidic alfisols, , Plos One., ISSN: 1932-6203, (2014), 9 (4) , e92400, DOI: 10.1371/journal.pone.0092400. (IF- 3.24) *Equal contribution 9. Chanchal Kumar, Kavita Yadav, G. Archana and G. Naresh Kumar (2013) 2-Ketogluconic acid secretion by incorporation of heterologous gluconate dehydrogenase (gad) operon in Enterobacter asburiae PSI3 improves mineral phosphate solubilization, Current Microbiology., ISSN: 0343-8651, (2013), 67 (3) 388-394, DOI: 10.1007/s00284-013-0372-z. (IF- 2.29) Patent: Tarun K Sharma, Jaya S. Tyagi, Chanchal Kumar, Abhijeet Dhiman, Ishara Datta. Isolated single stranded polynucleotides and uses thereof in diagnosis and treatment of Tuberculous Meningitis. Indian Patent Number 201611021901 Book Chapter: 1. Ajay Amit, Sudhir Yadav, Rajat Pratap Singh and Chanchal Kumar (2022) Development of RNA-Based Medicine for Colorectal Cancer: Current Scenario. In: Shukla, D., Vishvakarma, N.K., Nagaraju, G.P. (eds) Colon Cancer Diagnosis and Therapy Vol. 3. Springer, Cham. 2. Vivek Kumar Soni, Arundhati Mehta, Yashwant Kumar Ratre, Chanchal Kumar, Rajat Pratap Singh, Abhishek Kumar Srivastava, Navaneet Chaturvedi, Dhananjay Shukla, Sudhir Kumar Pandey and Naveen Kumar Vishvakarma (2022) Antineoplastic Effects of Curcumin Against Colorectal Cancer: Application and Mechanisms. In: Shukla, D., Vishvakarma, N.K., Nagaraju, G.P. (eds) Colon Cancer Diagnosis and Therapy Vol. 3. Springer, Cham. 3. Chanchal Kumar, Rajat Pratap Singh, Mrigendra Kumar Dwiwedi and Ajay Amit (2021) Immuno-modulating Mediators of Colon Cancer as Immuno-therapeutic: Mechanism and Potential. In: Nagaraju, G.P., Shukla, D., Vishvakarma, N.K. (eds) Colon Cancer Diagnosis and Therapy Vol. 1. Springer, Cham. 271-308. 4. Abhijeet Dhiman, Harleen Kaur, Chanchal Kumar, Yusra Ahmad, and Tarun Kumar Sharma (2019) Application of aptasensors in health care. Biosensors: Materials and Applications: Materials Research Foundations 47 1-50