Dr. Shivani Rai Paliwal

Assistant Professor

Work Experience

December 2011- Till date Teaching and Guiding students at Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, CG July 2009- December 2011 Senior Research Fellow, University Grant Commission, New Delhi, India March 2008-June 2009 Lecturer, ISF college of Pharmacy, Moga, India July 2007-March 2008 Lecturer, Globus College of Pharmacy, Bhopal, MP July 2004-June 2007 Junior Research Fellow, University Grant Commission, New Delhi

Area of Specialization

Pharmaceutics (Drug Delivery and Nanomedicine)

Projects & Patents

2020 Project entitled “Pre-clinical evaluation of phytoestrogen loaded bioadhesive zein-hyaluronic acid nanocomplex for chemopreventive action against breast cancer: formulation and optimization using box-behnken design" has been sanctioned by ICMR, New Delhi 2014 Project entitled “Development of targeted nanovector system(s) for intracellular delivery of Cytotoxic agents” has been recommended by Department of Science & Technology (SERB-DST) and completed.

Education

M. Pharm. PhD

Achievments/Awards/Honors

2022 Best Paper Award Year for the year 2020 by Guru Ghasidas Vishwavidhyalya, Bilaspur, CG. 2022 SERB International Research Experience Fellowship to visit Germany for 6 months 2011 Bioencapsulation Research Grant (BRG) to attend and presentation in XIX International Conference on Bioencapsulation, Amboise, France 2011 Travel Grant by Department of Science and Technology, India and Indian National Science Academy for attending ICBN 2010 at Singapore 2010 M. P. Young Scientist Award, 2010 by MP Council of Science and Technology, Bhopal, India 2010 M. P. Young Scientist Award, 2010inIst Women Science Congress by MP Council of Science and Technology, Bhopal, India 2009 Rudolf Cimdins Award 2009 by European Society of Biomaterials in 22nd European Conference on Biomaterials, Lausanne, Switzerland 2009 Travel Grant by Department of Biotechnology, India for attending 22nd ESB at Lausanne, Switzerland in 2009 2009 Senior Research Fellowship (SRF) from University Grant Commission, New Delhi, for PhD Project, India 2005 Junior Research Fellowship (JRF) from University Grant Commission for M. Pharm. Research Project, India

Publications

List of Publications: 1. Rishi Paliwal, Pramod Kumar, Akash Chaurasiya, Rameshroo Kenwat, Sumeet Katke, Shivani R Paliwal. Development of nanomedicines and nano-similars: recent advances in regulatory landscape. Current Pharmaceutical Design. 2022 Jan 1;28(2):165-77. (IF: 3.31) 2. Balak Das Kurmi, Shivani Rai Paliwal. Development and Optimization of TPGS based Stealth Liposome of Doxorubicin Using Box-Behnken Design: Characterization, Hemocompatibility and Cytotoxicity Evaluation in Breast Cancer Cells. Journal of liposome research. 2021, 1-17. (IF: 5.586 ) 3. Shivani R Paliwal, Rameshroo Kenwat, Sabyasachi Maiti, Rishi Paliwal. Nanotheranostics for Cancer Therapy and Detection: State of the Art, Current Pharmaceutical Design 26 (42), 5503-5517, 2020. (IF: 3.31 ) 4. Rishi Paliwal, Shivani Rai Paliwal, Rameshroo Kenwat, Balak Das Kurmi, Mukesh Kumar Sahu Solid lipid nanoparticles: a review on recent perspectives and patents. Expert Opinion on Therapeutic Patents 30 (3), 179-194, 2020. (IF: 6.74 ) 5. Pawan Tekchandani, Balak Das Kurmi, Rishi Paliwal, Shivani Rai Paliwal Galactosylated TPGS Micelles for Docetaxel Targeting to Hepatic Carcinoma: Development, Characterization, and Biodistribution Study. AAPS PharmSciTech. 2020 Jul;21(5):1-1. (IF: 4.026 ) 6. Balak Das Kurmi, Preeti Patel, Rishi Paliwal, Shivani Rai Paliwal. Molecular approaches for targeted drug delivery towards cancer: A concise review with respect to nanotechnology. Journal of Drug Delivery Science and Technology. 2020, 57, 101682. (IF: 5.062) 7. Balak Das Kurmi, Rishi Paliwal, Shivani Rai Paliwal. Dual cancer targeting using estrogen functionalized chitosan nanoparticles loaded with doxorubicin-estrone conjugate: A quality by design approach. International Journal of Biological Macromolecules. 2020, 164, 2881-2894. (IF: 8.025) 2020 Project entitled “Pre-clinical evaluation of phytoestrogen loaded bioadhesive zein-hyaluronic acid nanocomplex for chemopreventive action against breast cancer: formulation and optimization using box-behnken design" has been sanctioned by ICMR, New Delhi 2014 Project entitled “Development of targeted nanovector system(s) for intracellular delivery of Cytotoxic agents” has been recommended by Department of Science & Technology (SERB-DST) and completed. 8. Balak Das Kurmi Pawan Techchandani, Rishi Paliwal, Shivani Rai Paliwal.Transdermal Drug Delivery: Opportunities and Challenges for Controlled Delivery of Therapeutic Agents Using Nanocarriers. Current Drug Metabolism. 2017, 18,5,481-495. (IF: 3.408) 9. Pawan Techchandani, Balak Das Kurmi, Shivani Rai Paliwal. Nanomedicine to Deal with Cancer Cell Biology In Multi-Drug Resistance. Mini Reviews in Medicinal Chemistry. 2017, 17,18, 1793-1810. (IF: 3.737) 10. Rishi Paliwal, Shivani Rai Paliwal, Suresh P Vyas, Nanotherapeutics for cancer therapy and imaging, Mini Reviews in Medicinal Chemistry2017, 1. (IF: 3.737) 11. Shivani Rai Paliwal, Rishi Paliwal, G.P. Agrawal, S.P. Vyas. Hyaluronic acid modified pH-sensitive liposomes for targeted intracellular delivery of doxorubicin. J Liposome Res, 2016,26(4), 276-87. (IF: 5.586) 12. Balak Das Kurmi, Pawan Tekchandani, Rishi Paliwal and Shivani Rai Paliwal. Nanocarriers In Improved Heparin Delivery: Recent Updates. Current Pharmaceutical Design, Volume 21, Issue 42, 2015. (IF: 3.31) 13. Rishi Paliwal, Shivani Rai Paliwal, Suresh P Vyas, Role of Molecular Bioports in Oral Delivery of Biomacromolecules, Current Drug Therapy, 2014, 1-1. 14. Shivani Rai Paliwal, Rishi Paliwal and Suresh P Vyas. pH-sensitive liposomes: an update review. Drug Delivery. 2015, 22,3, 231-42. (IF: 6.819) 15. Shivani Rai Paliwal, Rishi Paliwal, G. P. Agrawal, S. P. Vyas, Targeted Breast Cancer Nanotherapeutics: Options And Opportunities With Estrogens Receptors, Critical Reviews™ in Therapeutic Drug Carrier Systems, 2012, 29(5), 421-446. (IF: 3.097) 16. Shivani R Paliwal, Rishi Paliwal, Harish C Pal, Ajit K Saxena, Praduman R Sharma, Prem N Gupta, Govind P Agrawal, Suresh P Vyas. Estrogen-Anchored pH-Sensitive Liposomes as Nanomodule Designed for Site-Specific Delivery of Doxorubicin in Breast Cancer Therapy, Mol Pharm. 2012 Jan 1;9(1):176-86. (IF: 5.364) 17. Rishi Paliwal, Shivani Rai Paliwal, G. P. Agrawal, S.P. Vyas, “Chitosan nanoconstructs for improved oral delivery of low molecular weight heparin: In vitro and in vivo evaluation” International Journal of Pharmaceutics, 2012 Jan 17;422(1-2):179-84. (IF: 6.51) 18. Rishi Paliwal, Shivani Rai Paliwal, G. P. Agrawal, S.P. Vyas, “Biomimetic Solid Lipid Nanoparticles for Oral Bioavailability Enhancement of Low Molecular Weight Heparin and Its Lipid Conjugates: In vitro and in vivo evaluation”, Molecular Pharmaceutics, 2011, 8(4):1314-21. (IF: 5.364) 19. Rishi Paliwal, Shivani Rai, S.P. Vyas, “Lipid drug conjugate (LDC) nanoparticles as autolymphotrophs for oral delivery of methotrexate”, Journal of Biomedical Nanotechnology, 2011, 7(1):130-131. (IF: 3.641) 20. Shivani Rai, Rishi Paliwal, S.P. Vyas, “Doxorubicin encapsulated nanocarriers for targeted delivery to estrogen responsive breast cancer” Journal of Biomedical Nanotechnology, 2011, 7(1):121-122. (IF: 3.641) 21. Shivani Rai Paliwal, Rishi Paliwal, G. P. Agrawal, S. P. Vyas, “Liposomal Nanomedicine in Breast Cancer Therapy” Nanomedicine (UK), 2011, 6(6):1085-100. (IF: 6.096) 22. Rishi Paliwal, Shivani Rai Paliwal, Govind Prasad Agrawal, S.P. Vyas. Recent advances in search of oral heparin therapeutics. Medicinal Research Reviews. 2012 32(2):388-409. (IF: 12.388) 23. Rishi Paliwal, Shivani Rai Paliwal, S. P. Vyas. Advances in effective vaccine development against hepatitis B: focus on mucosal immunization strategies. Therapeutic Delivery, 2010, Vol. 1, No. 3, Pages 397-410. 24. Sheetu Wadhwa, Rishi Paliwal, Shivani Rai Paliwal, S. P. Vyas, Hyaluronic Acid modified Chitosan Nanoparticles for Effective Management of Glaucoma: Development, characterization and evaluation, Journal of Drug Targeting, 2010, 18, 4, 292-302. (IF: 5.016) 25. Shivani Rai Paliwal, Rishi Paliwal, Neeraj Mishra, Abhinav Mehta, Suresh P. Vyas. A novel cancer targeting approach based on estrone anchored stealth liposome for sitespecific breast cancer therapy. Current Cancer Drug Target, 2010, 10, 3, 343-353. (IF: 2.907) 26. Bhuvaneshwar Vaidya, Amit K. Goyal, Kapil Khatri, Neeraj Mishra, Rishi Paliwal, Shivani Rai, Shailja Tiwari, S.P. Vyas, Bolaamphiphiles based novel liposomes: a possible approach for drug delivery, Int. J. Biomedical Nanoscience and Nanotechnology, 2010, 1, 2/3/4, 95-108. 27. Neeraj Mishra, Amit Kumar Goyal, Shailja Tiwari, Rishi Paliwal, Shivani Rai Paliwal, Bhuvneshwar Vaidya, Sharad Mangal, Madhu Gupta, Devyani Dube, Abhinav Mehta, Suresh P. Vyas. Recent advances in mucosal delivery of vaccine: Role of mucoadhesive/ biodegradable polymeric carriers. Expert Opinion on Therapeutic Patents. 2010, 20, 5, 661-679. (IF: 6.76) 28. Madhu Gupta; Amit K. Goyal; Shivani Rai Paliwal; Rishi Paliwal; Neeraj Mishra; Bhuvneshwar Vaidya; Devyani Dubey; S.K. Jain; S.P. Vyas. Development and characterization of effective topical liposomal system for localized treatment of cutaneous candidiasis. Journal of Liposome Research. 2010, 20, 4, 341-50. (IF: 5.586) 29. Daisy Arora, Amit K. Goyal, Shivani R. Paliwal, Bharat Khurana, Suresh P. Vyas, Oral Mucosal Immunization: Recent Advancement and Future Prospects, Current Immunology Reviews, 2010, 6, 3, 234-259. 30. Rishi Paliwal, Shivani Rai, Bhuvaneshwar Vaidya, Kapil Khatri, Amit K. Goyal, Neeraj Mishra, Abhinav Mehta, Suresh P. Vyas, Effect of lipid core material on characteristics of solid lipid nanoparticles designed for oral lymphatic delivery. Nanomedicine: Nanotechnology, Biology, and Medicine, 2009, 5, 2, 184-191. (IF: 6.458) 31. Rishi Paliwal, Shivani R Paliwal, Neeraj Mishra, Abhinav Mehta, S.P. Vyas “Engineered Chylomicron Mimicking Carrier Emulsome for Lymph Targeted Oral Delivery of Methotrexate”, International Journal of Pharmaceutics. 2009, 380, 1-2, 181- 188. (IF: 6.51) 32. Sheetu Wadhwa, Rishi Paliwal, Shivani R Paliwal, S. P. Vyas “Nanocarriers in Ocular Drug Delivery: An Update Review”, Current Pharmaceutical Design. 2009, 15, 23, 2724- 2750. (IF: 3.31) 33. Sheetu Wadhwa, Rishi Paliwal, Shivani Rai Paliwal, S. P. Vyas, Chitosan and its role in ocular therapeutics, Mini Reviews in Medicinal Chemistry, 2009, 9, 14, 1639-1647. (IF: 3.767) 34. Bhuvaneshwar Vaidya, Rishi Paliwal, Shivani Rai, Kapil Khatri, Amit K. Goyal, Neeraj Mishra, Suresh P Vyas, Cell-selective mitochondrial targeting: A new approach for cancer therapy, Cancer Therapy, 2009, 7, 141-148. 35. Amit K. Goyal, Kapil Khatri, Neeraj Mishra, Abhinav Mehta, Bhuvaneshwar Vaidya, Shailja Tiwari, Rishi Paliwal, Shivani Paliwal, Suresh P. Vyas, Development of Selfassembled Nanoceramic Carrier Construct(s) for Vaccine Delivery, Journal of Biomaterials Applications, 2009, 24, 1, 65-84. (IF: 2.712) 36. Shivani Rai, Rishi Paliwal, Bhuvaneshwar Vaidya, Prem N. Gupta, Kapil Khatri, Amit Goyal, S. P. Vyas, Solid lipid nanoparticles (SLNs) as a rising tool in drug delivery science: one step up in nanotechnology, Current Nanoscience, 4,1, 2008, 30-44. (IF: 1.51) 37. Shivani Rai, Rishi Paliwal, Bhuvaneshwar Vaidya, Kapil Khatri, Amit Goyal, Prem N. Gupta, S. P. Vyas, Targeted delivery of doxorubicin via estrone appended liposome, Journal Drug Targeting, 2008, 16, 6, 455- 463. (IF: 5.016) 38. Neeraj Mishra, Amit K. Goyal, Kapil Khatri, Bhuvaneshwar Vaidya, Rishi Paliwal, Shivani Rai, Abhinav Mehta, Shailja Tiwari, Shiva Vyas, Suresh P. Vyas, “Biodegradable Polymer Based Particulate Carrier(s) for the Delivery of Proteins and Peptides” Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2008, 7, 240-251. 39. Rishi Paliwal, Shivani Rai, Bhuvaneshwar Vaidya, Sunil Mahor, Prem N. Gupta, Amit Rawat, S.P. Vyas, Cell-selective Mitochondrial Targeting: Progress in Mitochondrial Medicine, Current Drug Delivery, 2007, 4, 3, 211-214. (IF: 3.758) 40. Shivani Rai, Rishi Paliwal, Bhuvaneshwar Vaidya, Prem N. Gupta, Sunil Mahor, Kapil Khatri, Amit K. Goyal, Amit Rawat, S.P. Vyas, Estrogen(s) and Analogs as a Non Immunogenic Endogenous Ligand in Targeted Drug/DNA Delivery, Current Medicinal Chemistry, 2007, 14, 2095-2105. (IF: 4.74) 41. Amit Rawat, Bhuvaneshwar Vaidya, Kapil Khatri, Amit K. Goyal, Prem N. Gupta, Rishi Paliwal, Shivani Rai, S.P. Vyas, Targeted intracellular delivery of therapeutics: An overview, Die Pharmazie, 2007, 62, 9, 643-58. (IF: 1.267) Recent books/book chapters/monographs: Guest Editor: Books: 1. Advances in Nanochemoprevention: Controlled Delivery of Phytochemical Bioactives R Paliwal, SR Paliwal Springer Nature, ISBN 978-981-15-9692-6, 2021. 2. Targeted nanomedicine for breast cancer therapy, 9780128244760, Elsevier, 2022. 3. Nanomedicine, Nanotheranostics and Nanobiotechnology: Fundamentals and Applications, CRC Press, (In Press). 1. Editor, Nanomedicine, Current Indian Science, Bentham Science Publishers since 2021 2. Special Issue of Mini-Review in Medicinal Chemistry “ Nanotherapeutics for Cancer Therapy and Imaging” (Published), 2017 3. Special Issue of Current Drug Therapy on “Role of Molecular Bioports in Oral Delivery of Biomacromolecules” (Published), 2014 Book Chapters: 1. R Kenwat, V Singh, SR Paliwal, Paliwal R. Photoresponsive nanocarriers for the delivery of bioactives. InSmart Polymeric Nano-Constructs in Drug Delivery 2023 Jan 1 (pp. 109-128). Academic Press. 2. S Naman, S Naryal, R Paliwal, SR Paliwal, A Baldi. Combating atherosclerosis with nanodrug delivery approaches: from bench side to commercialization. InDrug Delivery Systems for Metabolic Disorders 2022 Jan 1 (pp. 97-136). Academic Press. 3. A Malaiya, M Singhai, SR Paliwal, R Paliwal. Basics of targeted nanodrug delivery of chemotherapeutics for breast cancer therapy. InTargeted Nanomedicine for Breast Cancer Therapy 2022 Jan 1 (pp. 27-44). Academic Press. 4. BD Kurmi, R Paliwal, SR Paliwal. Cell-selective breast cancer targeting through estrogen receptors. InTargeted Nanomedicine for Breast Cancer Therapy 2022 Jan 1 (pp. 131-151). Academic Press. 5. R Kenwat, SR Paliwal, R Paliwal. Targeted breast cancer nanotheranostics. InTargeted Nanomedicine for Breast Cancer Therapy 2022 Jan 1 (pp. 441-464). Academic Press. 6. B Gajbe, BD Kurmi, R Kenwat, R Paliwal, SR Paliwal. Breast cancer: introduction. InTargeted Nanomedicine for Breast Cancer Therapy 2022 Jan 1 (pp. 3-26). Academic Press. 7. R Paliwal, A Chaurasiya, K Panchal, P Nayak, N Parveen, SR Paliwal. Engineering and functionalization of nanomaterials for theranostic applications in infectious diseases. InNanotheranostics for Treatment and Diagnosis of Infectious Diseases 2022 Jan 1 (pp. 45-71). Academic Press. 8. R Paliwal, K Sulakhiya, SR Paliwal, V Singh, R Kenwat, D Paramanik. Role of nanoparticles in neurotoxicity. InNanomedical Drug Delivery for Neurodegenerative Diseases 2022 Jan 1 (pp. 165-182). Academic Press. 9. R Paliwal, A Mamgain, R Kenwat, SR Paliwal. Reverse Engineering in Pharmaceutical. Micro-and Nanotechnologies-Based Product Development, 235, 2021. 10. R Paliwal, P Kumar, SR Paliwal, R Kenwat, O Schmid. Utility of Nanomaterials. Nanomaterials in Bionanotechnology: Fundamentals and Applications, 333, 2021. 11. R Paliwal, SR Paliwal, R Kenwat. Nanomedicine-based multidrug resistance reversal strategies in cancer therapy. Nano Drug Delivery Strategies for the Treatment of Cancers, 319-339, 2021. 12. Rishi Paliwal Shivani R Paliwal, Rameshuru, Balak D. Kurmi, Chitosan-based nanocarriers for ophthalmic applications. Polysaccharide Carriers for Drug Delivery,Editors: Sabyasachi Maiti Sougata Jana.Elsevier. 79-104. 2019 13. Shivani R Paliwal, Pawan Tekchandani, Balak D. Kurmi, Rishi Paliwal. Designing Nanocargos for Multi Drug Resistant Cancerous Cells: Strategies and Applications, 4 VolumeNanoBioMedicine book series. (In Press) 14. Shivani R Paliwal, Rishi Paliwal, Suresh P Vyas “Ligand appended liposomes for breast cancer therapy” Encyclopedia Of Biomedical Polymers And Polymeric Biomaterials, Taylor & Francis Group, LLC, New York, New York 10017 U.S.A. (In press) 15. Shivani R Paliwal, Rishi Paliwal, Suresh P Vyas “pH sensitive liposomes in drug delivery” In: Smart Materials for Drug Delivery, Royal Soceity of Chemistry, UK (In press). 16. Rishi Paliwal, Shivani R Paliwal, Suresh P Vyas “Novel Carrier(s) Based Vaccine Design against Hepatitis B: Recent Updates” In: Hepatitis B: New Research, Nova Science Publishers, (In press). 17. Suresh P Vyas, Rishi Paliwal, Shivani R Paliwal, “Chitosan-based Systems for Ocular Biopharmaceuticals Delivery” In: Chitosan-Based Systems for Biopharmaceuticals: Delivery, Targeting and Polymer Therapeutics Ed. Sarmento B and Neves JD, John Wiley & Sons, Ltd. 2012, pp. 243-254. 18. Suresh P Vyas, Rishi Paliwal, Shivani R Paliwal “Ocular Delivery of Proteins and Peptides” In: Protein and Peptide Delivery, Ed. Chris Walle, Elsevier. 2011, pp. 87-103 19. Suresh P Vyas, Rishi Paliwal, Shivani R Paliwal “Chitosan/Chitosan Derivatives as Carriers and Immunoadjuvants in Vaccine Delivery” In: Chitin, Chitosan, Oligosaccharides and Their Derivatives: Biological Activities and Applications, Ed. SN Kim CRC press. 2010, pp. 335-349. 20. Suresh P Vyas, Shivani R Paliwal, Rishi Paliwal “Targeted Drug Delivery” In: Lachman’s Industrial Pharmacy, Ed. Vyas SP and Khar RK, CBS Publishers, New Delhi, India. 21. Rishi Paliwal, Shivani R Paliwal, Suresh P Vyas, “Ocular Nanomedicine” In Nanocolloidal carriers in site specific and controlled drug delivery, CBS Publishers, New Delhi, India, 2010, 154-171. 22. Shivani R Paliwal, Rishi Paliwal, Suresh P Vyas, “Nanocarriers in Breast Cancer Therapy” In: Nanocolloidal carriers in site specific and controlled drug delivery, CBS Publishers, New Delhi, India, 2010, 554-577. 23. Rishi Paliwal, Shivani R Paliwal, Suresh P Vyas, “Nanocarriers: Toxicological Aspects” In Nanocolloidal carriers in site specific and controlled drug delivery, CBS Publishers, New Delhi, India, 661-674.