Dr. K. Kesavan

Assistant Professor

Work Experience

Teaching Experience: UG and PG: 12 Years Research Experience: 16 Years

Area of Specialization

Nanopharmaceuticals • Nano-sized dispersed systems for ocular drug delivery (Nanoparticles, Microemulsion, Nanoemulsion, nanomicelles, etc.) • Mucoadhesive nanocarrier drug delivery system for ocular delivery Novel drug delivery systems • Mucoadhesive ocular drug delivery system • Sustained ocular drug delivery to combat diseases in eye • Cationic nanocarriers for ocular drug delivery • Positively charged nanocarriers as non-viral vector for ocular gene therapy

Projects & Patents

Funding Agency: UGC, New Delhi UGC-BSR Startup Grant Grant No & Year Grant Received: File no. [No.F. 20-29(3)/2012(BSR)]dated 30.03.2013 Total : Rs. 6.00 lakh Topic Of The Project: Chitosan Coated Cationic Nanoemulsion: Ocular Drug Delivery System

Education

Ph.D: Indian Institute of Technology, Banaras Hindu University, Varanasi, U.P. M. Pharm: Bharathidasan University, Tiruchirappalli, Tamil Nadu B. Pharm: The Tamil Nadu Dr. M.G.R. Medical University, Chennai

Achievments/Awards/Honors

1. Received prestigious Genome Engineering/Editing Technology initiative (GETin) Overseas Fellowship 2018-19 funded by Department of Biotechnology (DBT), Govt. of India in association with Indo-U.S. Science & Technology Forum (IUSSTF). I had been selected one among the five candidates for this fellowship at the national level. 2. Awarded best paper in international conference on Fronterior in Nano Sciences, Technology and Applications on 20-22 December 2014 organized by Department of Physics, Sri Sathya Sai Institute of Higher Learning, Prashanthinilayam, Puttaparuthi, A.P. 3. Invited as distinguished speaker in international conference Phar-East 2018 Asia’s Pharma & Biotech Festival from 28 Feb-2018 to 3 March 2018. Suntec Singapore Convention & Exhibition Centre, Singapore. Organised by Terrapinn Pte Ltd, Singapore. 4. Invited as a speaker in national webinar National Webinar on “Current Trends in Nanotherapeutics for Ocular and Topical Drug Delivery” Organized by Faculty of Pharmacy, DIT University, Dehradun on 30-06-2021.

Publications

1. P Mohan, J Rajeswari, K Kesavan. TPGS-Chitosan Conjugated Mucoadhesive Micelles of Brinzolamide for Glaucoma Therapy: in vitro and in vivo Evaluation. Materialia, 101711. 2. Mohan P and Kesavan K. Cationic Polyelectrolyte Nanocapsules of Moxifloxacin for Microbial Keratitis Therapy: Development, Characterization, and Pharmacodynamic Study. AAPS PharmSciTech. (2021) 22: 195. [Impact factor – 3.246]. 3. Gautam N and Kesavan K. Phase Transition Microemulsion of Brimonidine Tartrate for Glaucoma Therapy: Preparation, Characterization and Pharmacodynamic Study. Curr Eye Res. (2021) 46: 1844-1852. ISSN: 0271-3683. [Impact factor – 1.754] 4. Dubey V, Mohan P, Dangi JS, Kesavan K. Brinzolamide loaded chitosan-pectin mucoadhesive nanocapsules for management of glaucoma: Formulation, characterization and pharmacodynamic study. Int J Biol Macromol. (2020) 152: 1224-1232. ISSN:0141-8130. [Impact factor – 6.953] 5. Kesavan K, Mohan P, Gautam N, Sheffield VC. Topical Ocular Delivery of Nanocarriers: A Feasible Choice for Glaucoma Management. Curr Pharm Des. (2020) 26: 5518-5532. ISSN: 1381-6128. [Impact factor – 3.116] 6. Tiwari R, Dubey V, Kesavan K.. Ocular Self-Microemulsifying Drug Delivery System (SMEDDS) of Prednisolone Improves Therapeutic Effectiveness in the Treatment of Experimental Uveitis. Ocular Immunology and Inflammation. (2019) 27(2): 303-311. ISSN: 0927-3948. [Impact factor – 2.112] 7. Kathle PK, Gautam N, Kesavan K.. Tamoxifen citrate loaded chitosan-gellan nanocapsules for breast cancer therapy: development, characterisation and in-vitro cell viability study. Journal of microencapsulation. (2018) 35(3): 292–300. ISSN: 0265-2048. [Impact factor – 2.287] 8. Bharti S.K. and Kesavan K.. Phase Transition W/O Microemulsions for Ocular Delivery: Evaluation of Antibacterial Activity in the Treatment of Bacterial Keratitis. Ocular Immunology and Inflammation. (2017) 25(4):463-474. ISSN: 0927-3948 [Impact factor – 2.112] 9. Kumari B and Kesavan K. Effect of Chitosan Coating on Microemulsion for Effective Dermal Clotrimazole Delivery. Pharm Dev. Technol. (2017) 22(4):617-626. ISSN: 1083-7450. [Impact factor – 2.169] 10. Kesavan K, Shri Kant, Singh PN, Pandit JK.. Therapeutic Effectiveness in the Treatment of Experimental Bacterial Keratitis with Ion-activated Mucoadhesive Hydrogel. Ocul Immunol Inflamm. (2016) 24(5):489-492. ISSN: 0927-3948. [Impact factor – 2.112] 11. Lanjhiyana SK, Bajpayee P, Kesavan K, Lanjhiyana S, Muthu MS.. Chitosan-sodium alginate blended polyelectrolyte complexes as potential multiparticulate carrier system: colon-targeted delivery and gamma scintigraphic imaging. Expert Opin Drug Deliv. (2013) 10: 5-15. ISSN: 1742-5247. [Impact factor – 5.79] Book Chapters Published 1. K Kesavan, N Gautam, O Parra-Marín, S Murugesan. Gene Therapy: A New Avenue for the Management of Ophthalmic Diseases. Nanoparticles and Nanocarriers Based Pharmaceutical Formulations, 395. 2. K Kesavan, P Mohan, SK Jain, O Parra-Marín, S Murugesan. Nanoemulsion: A Potential Carrier for Topical Drug Delivery. Nanoparticles and Nanocarriers Based Pharmaceutical Formulations, 230. 3. SK Jain, K Rajpoot, K Kesavan, A Yadav, U Gupta, PN Gupta. Targeting Potential of Nanocarriers for Efficient Treatment of H. Pylori Infection. Nanoparticles and Nanocarriers Based Pharmaceutical Formulations, 157.