Dr. Achal Mishra

Assistant Professor

Work Experience

15.6 Years

Area of Specialization

Pharmaceutical Chemistry

Projects & Patents

MRP, funded by Chhattisgarh Council of Science & Technology (CGCOST) topic QSAR analysis of some derivatives of quinoxaline as antimalarial agent”.

Education

Achievments/Awards/Honors

Received Best Publication Award In Shri Shankaracharya Technical Campus Faculty of Pharmaceutical Sciences, Bhilai (C.G.)

Publications

• Jaiswal P, Mishra A, Kesharwani D, Paul SD. Overview on ocular drug delivery through colloidal nano-suspension. Research Journal of Pharmacy and Technology. 2023 Mar 1;16(3):1533-9. • Sahu M, Choubey R, Sahu P, Mishra A. A comparative molecular docking study of Syzygiumcumini to understand the binding pattern with four different proteins Used for anti–diabetic activity. Eur. Chem. Bull. 2023, 12(Special Issue 1), 4981-4993 . • Rani M, Chauhan R, Sharma S, Singh A, Mishra A, Badwik H, Dwivedi J. Synthesis, Cannabinoid Receptor Targeted Molecular Docking of Some New Pyrazole Derivatives as Hypolipidemic and Anti-Obesity Agents. Indian Journal of Pharmaceutical Sciences. 2023 Feb 23;85(1):217-26. • Patel VK, Shirbhate E, Tiwari P, Kore R, Veerasamy R, Mishra A, Rajak H. Multi-targeted HDAC inhibitors as Anticancer Agents: Current Status and Future Prospective. Current Medicinal Chemistry. 30(24),2762 - 27952022 Sep 22. I.F.-4.74, 0929-8673 (print); 1875-533X (web) • Shirbhate E, Patel VK, Tiwari P, Kore R, Veerasamy R, Mishra A, Rajak H. Combination therapy for the treatment of alzheimer's disease: recent progress and future prospects. Curr Top Med Chem. 2022 Sep 7. doi: 10.2174/1568026622666220907114443. Epub ahead of print. PMID: 36082857.I.F.-3.57, 1568-0266 (print); 1873-4294 (web) • Jain S, Chauhan N, Bhardwaj A, Yadaw G, Singh MK, Mishra A. QSAR Modeling of α-Ketooxazole Motif Analogues as Potent Anti-Alzheimer Agents. YMER. 2022may5(21):624-640. ISSN No. 0044-0477 • Mishra A, Jha V, Rajak H. Molecular structural investigations of quinoxaline derivatives through 3D-QSAR, molecular docking, ADME prediction and pharmacophore modeling studies for the search of novel antimalarial agent. Journal of the Indian Chemical Society. 2022 Jan 5:100343. • Agrawal M, Dwivedi J, Kishore D, Jain S, Mishra A, Jain S, Sharma S. An Expeditious Approach to the Synthesis of Novel Quinolino and Diazacino Condensed Analogues of Azepino [3, 2-b] Carbazole-2-one of Medicinal Interest. Indian Journal of Pharmaceutical Education and Research. 2022 Jan 1;56(1):S89-97. • Mishra A, Vaishnav Y, Jha AK, Verma S. 3D QSAR analysis on quinoxaline derivatives as anti-malarial using K-nearest neighbour molecular field analysis. Indian Journal of Chemistry-Section B (IJC-B). 2021 Jun 29;60(5):727-31. • Mishra A, Waghela R. A Comparative Study of Approved Drugs for SARS-CoV-2 by Molecular Docking. Journal of Molecular Docking. 2021 Jun 30;1(1):25-31. • Dewangan D, Vaishnav Y, Mishra A, Jha AK, Verma S, Badwaik H. Synthesis, molecular docking, and biological evaluation of Schiff base hybrids of 1, 2, 4-triazole-pyridine as dihydrofolate reductase inhibitors. Current Research in Pharmacology and Drug Discovery. 2021 Jan 1;2:100024. • Arya R, Paliwal S, Gupta SP, Sharma S, Madan K, Mishra A, Verma K, Chauhan N. In-silico Studies and Biological Activity of Potential BACE-1 Inhibitors. Combinatorial Chemistry & High Throughput Screening. 2021 Jun 1;24(5):729-36. • Vaishnav Y, Dewangan D, Verma S, Mishra A, Thakur AS, Kashyap P, Verma SK. PPAR gamma targeted molecular docking and synthesis of some new amide and urea substituted 1, 3, 4‐thiadiazole derivative as antidiabetic compound. Journal of Heterocyclic Chemistry. 2020 May;57(5):2213-24. • Dewangan D, Nakhate K, Mishra A, Thakur AS, Rajak H, Dwivedi J, Sharma S, Paliwal S. Design, Synthesis, and Characterization of Quinoxaline Derivatives as a Potent Antimicrobial Agent. Journal of Heterocyclic Chemistry. 2019 Feb;56(2):566-78. • Arya R, Gupta SP, Paliwal S, Kesar S, Mishra A, Prabhakar YS. QSAR and molecular modeling studies on a series of pyrrolidine analogs acting as BACE-1 Inhibitors. Letters in Drug Design & Discovery. 2019 Jul 1;16(7):746-60. • Dhall E, Jain S, Mishra A, Dwivedi J, Sharma S. Synthesis and Evaluation of Some Phenyl Substituted Azetidine Containing 1, 2, 4‐triazole Derivatives as Antibacterial Agents. Journal of Heterocyclic Chemistry. 2018 Dec;55(12):2859-69. • Dewangan D, Nakhate KT, Verma VS, Nagori K, Badwaik H, Nair N, Tripathi DK, Mishra A. Synthesis and Molecular Docking Study of Novel Hybrids of 1, 3, 4‐Oxadiazoles and Quinoxaline as a Potential Analgesic and Anti‐Inflammatory Agents. Journal of Heterocyclic Chemistry. 2018 Dec;55(12):2901-10. • Misra A, Sharma S, Sharma D, Dubey S, Mishra A, Kishore D, Dwivedi J. Synthesis and molecular docking of pyrimidine incorporated novel analogue of 1, 5-benzodiazepine as antibacterial agent. Journal of Chemical Sciences. 2018 Mar;130(3):1-2. • Vaishnav Y, Thakur A, Kaur CD, Verma S, Mishra A, Jain SK, Ghode P. QSAR Analysis of some N, N-diphenyl urea derivatives as CCR5 Receptor Antagonist. Research Journal of Pharmacy and Technology. 2018;11(9):3802-10. • Paliwal S, Sharma S, Dwivedi J, Mishra A. Synthesis of Novel Substituted Phenyl‐3‐Hydrazinyl‐Quinoxaline‐2‐Amine Derivatives: Evaluation of Antimicrobial Activity and Its Molecular Docking Studies. Journal of Heterocyclic Chemistry. 2017 Nov;54(6):3689-95. • Mishra A, Paliwal S, Sharma S, Dwivedi J. Synthesis and Molecular Docking Studies of Some New Quinoxaline Derivatives as Potential Antimicrobial Agents. INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY. 2017 Jul 1;27(3):249-54. • Sanmati KJ, Achal M. 3D QSAR Analysis on Isatin Derivatives as Carboxyl Esterase Inhibitors Using K-Nearest Neighbor Molecular Field Analysis. J TheorComput Sci. 2015 May;2(2):1-2. • Achal Mishra, BhavnaYadav, ShekharVerma, YashwantSwarnakar, A.K. Jha, PermanandVerma, DevendraSahu. A Short Review on Concept and Types of Combinatorial Chemistry, Asian Journal of Research in Chemistry, 7, 2, 2014, 243-248. 0974-4150(Online), 0974-4169(Print). • Achal Mishra, Takesh Kumar Nagwanshi, RemanlalSahu, Lokendra Kumar Verma, RuchiYadav. A review on quinoxaline - pharmacophore and derivatives with diverse biological properties, world journal of pharmacy and pharmaceutical sciences, 2,6, 2013, 6486-6506. ISSN- 2278-4357. • Naveen K. Mahobia, Sanmati K. Jain, Roshan Patel, Sudarshan K. Singh , Achal Mishra, RavindraDhardubey. 3D QSAR Analysis of Some Piperidinyl Amide and Ureas as CCR5 Antagonist, Journal of Pharmacy Research 5, 9, 2012, 4706-4709. ISSN: 0974-6943, • Achal Mishra, Harish Rajak, Green Chemistry: an insight into recent advances and their application in academics and research, India journal of technical education (CSIR), 35, 2012, 22-28. ISSN- 0971-3034. • DhansayDewangan, Achal Mishra, Alok Pandey, ShekharVerma, RavindraDharDubey. Synthesis of Schiff bases of 2-amino-5-aryl-1, 3, 4-thiadiazole And Its Analgesic, Anti-Inflammatory, Anti-Bacterial and Anti-Tubercular Activity”, International Journal of ChemTech Research, 3, 1, 2011, 178-184. ISSN (online) 2455-9555, (print) 0974-4290. • S. S. Pancholi, RajkumarAgrawal, Achal Mishra. QSAR on Heteroaryl-Phenyl-Substituted Pyrazole Derivatives as Selective and Potent Canine COX-2 Inhibitors, Current Pharmaceutical Science, 02, 2011, 68-76. ISSN-2250-2688. • Sanmati K. Jain, Ravindra D. Dubey, S. Mallick, S. Nag, A. Yadav, Achal Mishra Naveen K. Mahobia. 2D and 3D-QSAR Analysis of some 1, 3-disubstituted Urea Derivativesfor Anti proliferative Activity. Der PharmaChemica, 2, 6, 2010, 125-133. ISSN 0975-413x. • Naveen K. Mahobia, Roshan D. Patel, Naheed W. Sheikh, Sudarshan K. Singh , Achal Mishra, RavindraDhardubey. Validation Method Used In Quantitative Structure Activity Relationship, Der PharmaChemica, 2, 5, 2010, 260-271. ISSN 0975-413x. • ParmanandVerma, Alpna Ram, Arvind Kumar Jha, Achal Mishra, Alok Thakur. Phosphatidylcholine: a revolution in drug delivery technology, international journal of pharmaceutical sciences and research, 2010, 1, 2. 2010 ISSN (Online): 0975-8232, ISSN (Print): 2320-5148. Recent Books/Book chapters/Monographs etc: • Isatine derivative as human carboxylestarase inhibitors: an approach towards 3D-QSAR, pharmacophore and moleculardocking, B.P. International Publication. Current Aspects in Pharmaceutical Research and Development Vol. 2, 18 September 2021, Page1-21, https://doi.org/10.9734/bpi/caprd/v2/12980D • A Molecular Docking Study bring Golden Era in Pharmaceutical Drug Design and Chemical Engineering Process, Bharti Publication, India. • Pharmaceutical Importance of Copolymers: A Special Note on Eudragit,AkiNikPublications, New Delhi, Page No.-31-46, ISBN: 978-93-5570-305-7, DOI: https://doi.org/10.22271/ed.book.1751. • A Text book of computer aided drug design, Dr. P.K Publication, ISBN NO.- 97893-94919-327. Advanced Medicinal Chemistry, IIP iterative International Publishers, 2023, ISBN No.-978-93-5747-861-8.